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von Hippel-Lindau Protein Maintains Metabolic Balance to Regulate the Survival of Naive B Lymphocytes

B lymphocytes undergo metabolic reprogramming upon activation to meet the bioenergetic demands for proliferation and differentiation. Yet, little is known if and how the fate of naive B cells is metabolically regulated. Here, we specifically delete von Hippel-Lindau protein (VHL) in B cells using CD...

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Detalles Bibliográficos
Autores principales: Xu, Shengli, Huo, Jianxin, Huang, Yuhan, Aw, Melissa, Chen, Shuwen, Mak, Shiya, Yip, Lian Yee, Ho, Ying Swan, Ng, Sze Wai, Tan, Andy Hee-Meng, Lee, Alison, Ou, Xijun, Lam, Kong-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660606/
https://www.ncbi.nlm.nih.gov/pubmed/31351078
http://dx.doi.org/10.1016/j.isci.2019.07.002