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Systemic TLR2 tolerance enhances central nervous system remyelination
BACKGROUND: Multiple sclerosis (MS) is a central nervous system (CNS) autoimmune disease characterized by both inflammatory demyelination and impaired remyelination. Studies indicate that Toll-like receptor 2 (TLR2) signaling contributes to both the inflammatory component and the defective remyelina...
Autores principales: | Wasko, Nicholas J., Kulak, Meghan Horne, Paul, Debayon, Nicaise, Alexandra M., Yeung, Stephen T., Nichols, Frank C., Khanna, Kamal M., Crocker, Stephen, Pachter, Joel S., Clark, Robert B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660683/ https://www.ncbi.nlm.nih.gov/pubmed/31351476 http://dx.doi.org/10.1186/s12974-019-1540-2 |
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