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Metformin mediates neuroprotection and attenuates hearing loss in experimental pneumococcal meningitis

BACKGROUND: Pneumococcal meningitis is associated with high risk of neurological sequelae such as cognitive impairment and hearing loss. These sequelae are due to parenchymal brain and inner ear damage primarily induced by the excessive inflammatory reaction in response to bacterial brain invasion....

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Detalles Bibliográficos
Autores principales: Muri, Lukas, Le, Ngoc Dung, Zemp, Jonas, Grandgirard, Denis, Leib, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660697/
https://www.ncbi.nlm.nih.gov/pubmed/31351490
http://dx.doi.org/10.1186/s12974-019-1549-6