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Metformin mediates neuroprotection and attenuates hearing loss in experimental pneumococcal meningitis
BACKGROUND: Pneumococcal meningitis is associated with high risk of neurological sequelae such as cognitive impairment and hearing loss. These sequelae are due to parenchymal brain and inner ear damage primarily induced by the excessive inflammatory reaction in response to bacterial brain invasion....
Autores principales: | Muri, Lukas, Le, Ngoc Dung, Zemp, Jonas, Grandgirard, Denis, Leib, Stephen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660697/ https://www.ncbi.nlm.nih.gov/pubmed/31351490 http://dx.doi.org/10.1186/s12974-019-1549-6 |
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