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Protein synthesis rates and ribosome occupancies reveal determinants of translation elongation rates
Although protein synthesis dynamics has been studied both with theoretical models and by profiling ribosome footprints, the determinants of ribosome flux along open reading frames (ORFs) are not fully understood. Combining measurements of protein synthesis rate with ribosome footprinting data, we he...
Autores principales: | Riba, Andrea, Di Nanni, Noemi, Mittal, Nitish, Arhné, Erik, Schmidt, Alexander, Zavolan, Mihaela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660795/ https://www.ncbi.nlm.nih.gov/pubmed/31292258 http://dx.doi.org/10.1073/pnas.1817299116 |
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