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Comparative genomic analysis suggests that the sperm-specific sodium/proton exchanger and soluble adenylyl cyclase are key regulators of CatSper among the Metazoa
BACKGROUND: CatSper is a sperm-specific calcium ion (Ca(2+)) channel, which regulates sperm flagellar beating by tuning cytoplasmic Ca(2+) concentrations. Although this Ca(2+) channel is essential for mammalian fertilization, recent bioinformatics analyses have revealed that genes encoding CatSper a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660944/ https://www.ncbi.nlm.nih.gov/pubmed/31372239 http://dx.doi.org/10.1186/s40851-019-0141-3 |