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Comparative genomic analysis suggests that the sperm-specific sodium/proton exchanger and soluble adenylyl cyclase are key regulators of CatSper among the Metazoa

BACKGROUND: CatSper is a sperm-specific calcium ion (Ca(2+)) channel, which regulates sperm flagellar beating by tuning cytoplasmic Ca(2+) concentrations. Although this Ca(2+) channel is essential for mammalian fertilization, recent bioinformatics analyses have revealed that genes encoding CatSper a...

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Detalles Bibliográficos
Autores principales: Romero, Francisco, Nishigaki, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660944/
https://www.ncbi.nlm.nih.gov/pubmed/31372239
http://dx.doi.org/10.1186/s40851-019-0141-3