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Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis
BACKGROUND: Subchondral bone (SCB) thickening is one of the earliest detectable changes in osteoarthritic joints and is considered a potential trigger for subsequent articular cartilage degeneration. In this manuscript, we examine whether disruption to the SCB osteocyte network contributes to the in...
Autores principales: | Staines, Katherine A., Ikpegbu, Ekele, Törnqvist, Anna E., Dillon, Scott, Javaheri, Behzad, Amin, Anish K., Clements, Dylan N., Buttle, David J., Pitsillides, Andrew A., Farquharson, Colin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661085/ https://www.ncbi.nlm.nih.gov/pubmed/31351471 http://dx.doi.org/10.1186/s12891-019-2731-9 |
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