Cargando…
Physicochemical and Pharmacokinetic Profiles of Gadopiclenol: A New Macrocyclic Gadolinium Chelate With High T1 Relaxivity
OBJECTIVES: We aimed to evaluate gadopiclenol, a newly developed extracellular nonspecific macrocyclic gadolinium-based contrast agent (GBCA) having high relaxivity properties, which was designed to increase lesion detection and characterization by magnetic resonance imaging. METHODS: We described t...
Autores principales: | Robic, Caroline, Port, Marc, Rousseaux, Olivier, Louguet, Stéphanie, Fretellier, Nathalie, Catoen, Sarah, Factor, Cécile, Le Greneur, Soizic, Medina, Christelle, Bourrinet, Philippe, Raynal, Isabelle, Idée, Jean-Marc, Corot, Claire |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661244/ https://www.ncbi.nlm.nih.gov/pubmed/30973459 http://dx.doi.org/10.1097/RLI.0000000000000563 |
Ejemplares similares
-
Small Brain Lesion Enhancement and Gadolinium Deposition in the Rat Brain: Comparison Between Gadopiclenol and Gadobenate Dimeglumine
por: Violas, Xavier, et al.
Publicado: (2022) -
Gadolinium Retention, Brain T1 Hyperintensity, and Endogenous Metals: A Comparative Study of Macrocyclic Versus Linear Gadolinium Chelates in Renally Sensitized Rats
por: Rasschaert, Marlène, et al.
Publicado: (2018) -
Analytical Interference in Serum Iron Determination Reveals Iron Versus Gadolinium Transmetallation With Linear Gadolinium-Based Contrast Agents
por: Fretellier, Nathalie, et al.
Publicado: (2014) -
T1-Weighted Hypersignal in the Deep Cerebellar Nuclei After Repeated Administrations of Gadolinium-Based Contrast Agents in Healthy Rats: Difference Between Linear and Macrocyclic Agents
por: Robert, Philippe, et al.
Publicado: (2015) -
Multimodal Imaging Study of Gadolinium Presence in Rat Cerebellum: Differences Between Gd Chelates, Presence in the Virchow-Robin Space, Association With Lipofuscin, and Hypotheses About Distribution Pathway
por: Rasschaert, Marlène, et al.
Publicado: (2018)