Ropinirole hydrochloride remedy for amyotrophic lateral sclerosis – Protocol for a randomized, double-blind, placebo-controlled, single-center, and open-label continuation phase I/IIa clinical trial (ROPALS trial)

INTRODUCTION: Amyotrophic lateral sclerosis (ALS) is an intractable and incurable neurological disease. It is a progressive disease characterized by muscle atrophy and weakness caused by selective vulnerability of upper and lower motor neurons. In disease research, it has been common to use mouse mo...

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Detalles Bibliográficos
Autores principales: Morimoto, Satoru, Takahashi, Shinichi, Fukushima, Komei, Saya, Hideyuki, Suzuki, Norihiro, Aoki, Masashi, Okano, Hideyuki, Nakahara, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661418/
https://www.ncbi.nlm.nih.gov/pubmed/31384636
http://dx.doi.org/10.1016/j.reth.2019.07.002

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