Arsenic sulfide nanoformulation induces erythroid differentiation in chronic myeloid leukemia cells through degradation of BCR-ABL

BACKGROUND: Chronic myeloid leukemia (CML) is a myeloproliferative disorder due to the existence of BCR-ABL fusion protein that allows the cells to keep proliferating uncontrollably. Although tyrosine kinase inhibitors can inhibit the activity of BCR-ABL fusion protein to trigger the cells apoptosis...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Tao, Wen, Tao, Li, Hongmin, Han, Bing, Hao, Suisui, Wang, Chuan, Ma, Qiang, Meng, Jie, Liu, Jian, Xu, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661449/
https://www.ncbi.nlm.nih.gov/pubmed/31413564
http://dx.doi.org/10.2147/IJN.S207298

Ejemplares similares

Ejemplares similares