Effects of Stuffer DNA on the Suppression of Choroidal Neovascularization by a rAAV Expressing a mTOR-Inhibiting shRNA

Choroidal neovascularization (CNV) is the defining characteristic of the wet subtype of age-related macular degeneration (AMD), which is a rapidly growing global health problem. Previously, we had demonstrated the therapeutic potential of gene therapy against CNV using short hairpin RNA (shRNA) deli...

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Detalles Bibliográficos
Autores principales: Lee, Steven Hyun Seung, Chang, HeeSoon, Kim, Hee Jong, Choi, Jun-Sub, Kim, Jin, Kim, Ji Hyun, Woo, Ha-Na, Nah, Seung Kwan, Jung, Sang Joon, Lee, Joo Yong, Park, Keerang, Park, Tae Kwann, Lee, Heuiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661460/
https://www.ncbi.nlm.nih.gov/pubmed/31380463
http://dx.doi.org/10.1016/j.omtm.2019.06.004

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