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Efficient biosynthesis of 2-keto-D-gluconic acid by fed-batch culture of metabolically engineered Gluconobacter japonicus

2-keto-d-gluconic acid (2-KGA) is a key precursor for synthesising vitamin C and isovitamin C. However, phage contamination is as constant problem in industrial production of 2-KGA using Pseudomonas fluorescens. Gluconobacter holds promise for producing 2-KGA due to impressive resistance to hyperton...

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Detalles Bibliográficos
Autores principales:	Zeng, Weizhu, Cai, Wen, Liu, Li, Du, Guocheng, Chen, Jian, Zhou, Jingwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	KeAi Publishing 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661466/ https://www.ncbi.nlm.nih.gov/pubmed/31384676 http://dx.doi.org/10.1016/j.synbio.2019.07.001

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