Cargando…

Protocol for a systematic scoping review of reasons given to justify the performance of randomised controlled trials

INTRODUCTION: Randomised controlled trials (RCTs) are widely viewed to generate the most reliable medical knowledge. However, RCTs are not always scientifically necessary and therefore not always ethical. Unfortunately, it is not clear when an RCT is not necessary or how this should be established....

Descripción completa

Detalles Bibliográficos
Autores principales:	Dewar, Brian, Fedyk, Mark, Jurkovic, Lucas, Chevrier, Stephanie, Rodriguez, Rosendo, Kitto, Simon C, Saginur, Raphael, Shamy, Michel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Ethics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661623/ https://www.ncbi.nlm.nih.gov/pubmed/31350242 http://dx.doi.org/10.1136/bmjopen-2018-027575

Ejemplares similares

What do we talk about when we talk about “equipoise”? Stakeholder interviews assessing the use of equipoise in clinical research ethics
por: Dewar, Brian, et al.
Publicado: (2023)

Rationalisations for women-only randomised controlled trials in conditions that affect both sexes: a scoping review protocol
por: Matthewson, Ainsley, et al.
Publicado: (2021)

Advanced consent for participation in acute care randomised control trials: protocol for a scoping review
por: Niznick, Naomi, et al.
Publicado: (2020)

Advance consent for participation in randomised controlled trials for emergency conditions: a scoping review
por: Niznick, Naomi, et al.
Publicado: (2023)

Concerning Pathophysiology and Justifying Clinical Trials
por: Shamy, Michel, et al.
Publicado: (2021)

Registration audit of clinical trials given a favourable opinion by UK research ethics committees
por: Denneny, Carla, et al.
Publicado: (2019)

Determining the level of data sharing, and number of publications, from research databases that have been given a favourable opinion by UK research ethics committees
por: Trace, Samantha, et al.
Publicado: (2020)

Protocol for a scoping review about ethics in transition programmes for adolescents and young adults with neurodisabilities
por: Bogossian, Aline, et al.
Publicado: (2018)

Factors contributing to practitioner choice when declining involvement in legally available care: A scoping protocol
por: Brown, Janine, et al.
Publicado: (2018)

Strengthening ethics committees for health-related research in sub-Saharan Africa: a scoping review protocol
por: Thurtle, Val, et al.
Publicado: (2021)

Predatory conferences: a systematic scoping review
por: Godskesen, Tove, et al.
Publicado: (2022)

Prospective registration trends, reasons for retrospective registration and mechanisms to increase prospective registration compliance: descriptive analysis and survey
por: Hunter, Kylie Elizabeth, et al.
Publicado: (2018)

Do protocols for new randomised trials take previous similar trials into account? Cohort study of contemporary trial protocols
por: Paludan-Müller, Asger Sand, et al.
Publicado: (2019)

Four reasons why too many informed consents to clinical research are invalid: a critical analysis of current practices
por: Wisgalla, Anne, et al.
Publicado: (2022)

The Lived Experience Of Participants in an African RandomiseD trial (LEOPARD): protocol for an in-depth qualitative study within a multisite randomised controlled trial for HIV-associated cryptococcal meningitis
por: Lawrence, David S, et al.
Publicado: (2021)

Public involvement and engagement in big data research: protocol for a scoping review and a systematic review of delivery and effectiveness of strategies for involvement and engagement
por: Teodorowski, Piotr, et al.
Publicado: (2021)

Ethical frameworks in clinical research processes during COVID-19: a scoping review
por: Kasherman, Lawrence, et al.
Publicado: (2021)

Best Case/Worst Case: protocol for a multisite randomised clinical trial of a scenario planning intervention for patients with kidney failure
por: Haug, Karlie, et al.
Publicado: (2022)

Is mandating elective single embryo transfer ethically justifiable in young women?
por: Tremellen, Kelton, et al.
Publicado: (2016)

Informed consent in cluster randomised trials: a guide for the perplexed
por: Nix, Hayden P, et al.
Publicado: (2021)

Are patients accurate forecasters of their emotional response to medical conditions? A scoping review on affective forecasting
por: van den Bosch, G J, et al.
Publicado: (2021)

Exploring the experiences of substitute decision-makers with an exception to consent in a paediatric resuscitation randomised controlled trial: study protocol for a qualitative research study
por: Parker, Melissa J, et al.
Publicado: (2016)

Individualisation, personalisation and person-centredness in mental healthcare: a scoping review of concepts and linguistic network visualisation
por: Mayer, Gwendolyn, et al.
Publicado: (2023)

Compliance with ethical standards in the reporting of donor sources and ethics review in peer-reviewed publications involving organ transplantation in China: a scoping review
por: Rogers, Wendy, et al.
Publicado: (2019)

Consent processes in cluster-randomised trials in residential facilities for older adults: a systematic review of reporting practices and proposed guidelines
por: DiazOrdaz, Karla, et al.
Publicado: (2013)

Parental comprehension of the benefits/risks of first-line randomised clinical trials in children with solid tumours: a two-stage cross-sectional interview study
por: Chappuy, Hélène, et al.
Publicado: (2013)

Reasons for and time to retraction of genetics articles published between 1970 and 2018
por: Dal-Ré, Rafael, et al.
Publicado: (2019)

Benefit of carotid revascularisation for women with symptomatic carotid stenosis: protocol for a systematic review
por: Bereznyakova, Olena, et al.
Publicado: (2019)

Protocol for Deferral of Consent in Acute Stroke Trials
por: Faris, Hannah, et al.
Publicado: (2023)

Author misrepresentation of institutional affiliations: protocol for an exploratory case study
por: Bachelet, Vivienne C, et al.
Publicado: (2019)

Disparities in the completion of steps to kidney transplantation: protocol for a systematic review
por: Traino, Heather M, et al.
Publicado: (2015)

Published patterns of spin in biomedical literature: a protocol for a meta-research study
por: Su, Naichuan, et al.
Publicado: (2021)

Effectiveness of interventions on healthcare professionals’ understanding and use of conscience: a systematic review protocol
por: Lamb, Christina, et al.
Publicado: (2022)

Family bereavement and organ donation in Spain: a mixed method, prospective cohort study protocol
por: Martinez-Lopez, Maria Victoria, et al.
Publicado: (2023)

Clinical ethics support services in paediatric practice: protocol for a mixed studies systematic review on structures, interventions and outcomes
por: Dittborn, Mariana, et al.
Publicado: (2022)

Developing an ethical framework-guided instrument for assessing bias in EHR-based Big Data studies: a research protocol
por: Qiao, Shan, et al.
Publicado: (2023)

CARING FUTURES: a study protocol for transdisciplinary qualitative research on technology-mediated care practices and theory development for ethics of care
por: Ramvi, Ellen, et al.
Publicado: (2021)

How do community advisory boards fulfil their ethical role in HIV clinical trials? A protocol for a systematic review of qualitative evidence
por: Pancras, Godwin, et al.
Publicado: (2020)

Cross-sectional assessment of patient attitudes towards participation in clinical trials: does making results publicly available matter?
por: Jones, Christopher W, et al.
Publicado: (2016)

A cross-sectional examination of conflict-of-interest disclosures of physician-authors publishing in high-impact US medical journals
por: Baraldi, James H, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_girtb6ueisfu9kh8e93g9dle6c