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In silico design and synthesis of hesperitin derivatives as new xanthine oxidase inhibitors
BACKGROUND: Hesperitin, a naturally occurring flavonoid was hybridized with phenolic acids to evaluate its potential to inhibit the activity of xanthine oxidase (XO), a key enzyme which catalyses xanthine to uric acid which is found to be associated with gout and many life style related disorders. O...
Autores principales: | Malik, Neelam, Dhiman, Priyanka, Khatkar, Anurag |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661729/ https://www.ncbi.nlm.nih.gov/pubmed/31384801 http://dx.doi.org/10.1186/s13065-019-0571-1 |
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