A novel synthesis, X-ray analysis and computational studies of (Z)-ethyl 2-((Z)-5-((dimethylamino)methylene)- 4-oxo-3-phenylthiazolidin-2-ylidene)acetate as a potential anticancer agent

BACKGROUND: 4-Thiazolidinone ring is reported to have almost all types of biological activities. Also, it present in many marketed drugs. RESULTS: Ethyl acetoacetate reacted with phenyl isothiocyanate and ethyl chloroacetate in presence of K(2)CO(3) and DMF to afford the thiazolidinone derivative 5....

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Detalles Bibliográficos
Autores principales: Mabkhot, Yahia N., Alharbi, Mohammed M., Al-Showiman, Salim. S., Soliman, Saied M., Kheder, Nabila A., Frey, Wolfgang, Asayari, Abdulrhman, Bin Muhsinah, Abdullatif, Algarni, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661753/
https://www.ncbi.nlm.nih.gov/pubmed/31384783
http://dx.doi.org/10.1186/s13065-019-0554-2

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