Bone Regeneration: A Magnesium‐Enriched 3D Culture System that Mimics the Bone Development Microenvironment for Vascularized Bone Regeneration (Adv. Sci. 12/2019)

Inspired by the correlation between MagT1 and embryonic bone development, a magnesium‐enriched 3D culture system is fabricated to provide embryonic‐like microenvironment for stem cells in article number 1900209 by Wenjie Zhang, Xinquan Jiang, and co‐workers. Mg(2+) via MagT1 stimulates both osteogen...

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Detalles Bibliográficos
Autores principales: Lin, Sihan, Yang, Guangzheng, Jiang, Fei, Zhou, Mingliang, Yin, Shi, Tang, Yanmei, Tang, Tingting, Zhang, Zhiyuan, Zhang, Wenjie, Jiang, Xinquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662061/
http://dx.doi.org/10.1002/advs.201970069
Descripción
Sumario:Inspired by the correlation between MagT1 and embryonic bone development, a magnesium‐enriched 3D culture system is fabricated to provide embryonic‐like microenvironment for stem cells in article number 1900209 by Wenjie Zhang, Xinquan Jiang, and co‐workers. Mg(2+) via MagT1 stimulates both osteogenic differentiation and neovascularization. An obvious vascularized bone regeneration is achieved in vivo using such magnesium‐enriched cell vehicles. [Image: see text]

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