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PI3Kgamma Inhibitor Attenuates Immunosuppressive Effect of Poly(l‐Glutamic Acid)‐Combretastatin A4 Conjugate in Metastatic Breast Cancer

Vascular disrupting agents (VDAs) have great potential for cancer treatment. Poly(l‐glutamic acid)‐combretastatin A4 conjugate (PLG‐CA4) is a novel class of VDAs. Though it has notable antitumor activity, it can induce host immune responses that promote tumor growth. Here, PLG‐CA4 induces the polari...

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Detalles Bibliográficos
Autores principales:	Qin, Hanjiao, Yu, Haiyang, Sheng, Jiyao, Zhang, Dawei, Shen, Na, Liu, Linlin, Tang, Zhaohui, Chen, Xuesi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662090/ https://www.ncbi.nlm.nih.gov/pubmed/31380170 http://dx.doi.org/10.1002/advs.201900327

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