Gene expression models based on transcription factor binding events confer insight into functional cis-regulatory variants

MOTIVATION: Deciphering the functional roles of cis-regulatory variants is a critical challenge in genome analysis and interpretation. It has been hypothesized that altered transcription factor (TF) binding events are a central mechanism by which cis-regulatory variants impact gene expression levels...

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Detalles Bibliográficos
Autores principales: Shi, Wenqiang, Fornes, Oriol, Wasserman, Wyeth W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662294/
https://www.ncbi.nlm.nih.gov/pubmed/30541050
http://dx.doi.org/10.1093/bioinformatics/bty992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662294/
https://www.ncbi.nlm.nih.gov/pubmed/30541050
http://dx.doi.org/10.1093/bioinformatics/bty992

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