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Gene expression models based on transcription factor binding events confer insight into functional cis-regulatory variants
MOTIVATION: Deciphering the functional roles of cis-regulatory variants is a critical challenge in genome analysis and interpretation. It has been hypothesized that altered transcription factor (TF) binding events are a central mechanism by which cis-regulatory variants impact gene expression levels...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662294/ https://www.ncbi.nlm.nih.gov/pubmed/30541050 http://dx.doi.org/10.1093/bioinformatics/bty992 |