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Review on Acoustic Droplet Vaporization in Ultrasound Diagnostics and Therapeutics
Acoustic droplet vaporization (ADV) is the physical process in which liquid undergoes phase transition to gas after exposure to a pressure amplitude above a certain threshold. In recent years, new techniques in ultrasound diagnostics and therapeutics have been developed which utilize microformulatio...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662494/ https://www.ncbi.nlm.nih.gov/pubmed/31392217 http://dx.doi.org/10.1155/2019/9480193 |
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author | Loskutova, Ksenia Grishenkov, Dmitry Ghorbani, Morteza |
author_facet | Loskutova, Ksenia Grishenkov, Dmitry Ghorbani, Morteza |
author_sort | Loskutova, Ksenia |
collection | PubMed |
description | Acoustic droplet vaporization (ADV) is the physical process in which liquid undergoes phase transition to gas after exposure to a pressure amplitude above a certain threshold. In recent years, new techniques in ultrasound diagnostics and therapeutics have been developed which utilize microformulations with various physical and chemical properties. The purpose of this review is to give the reader a general idea on how ADV can be implemented for the existing biomedical applications of droplet vaporization. In this regard, the recent developments in ultrasound therapy which shed light on the ADV are considered. Modern designs of capsules and nanodroplets (NDs) are shown, and the material choices and their implications for function are discussed. The influence of the physical properties of the induced acoustic field, the surrounding medium, and thermophysical effects on the vaporization are presented. Lastly, current challenges and potential future applications towards the implementation of the therapeutic droplets are discussed. |
format | Online Article Text |
id | pubmed-6662494 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-66624942019-08-07 Review on Acoustic Droplet Vaporization in Ultrasound Diagnostics and Therapeutics Loskutova, Ksenia Grishenkov, Dmitry Ghorbani, Morteza Biomed Res Int Review Article Acoustic droplet vaporization (ADV) is the physical process in which liquid undergoes phase transition to gas after exposure to a pressure amplitude above a certain threshold. In recent years, new techniques in ultrasound diagnostics and therapeutics have been developed which utilize microformulations with various physical and chemical properties. The purpose of this review is to give the reader a general idea on how ADV can be implemented for the existing biomedical applications of droplet vaporization. In this regard, the recent developments in ultrasound therapy which shed light on the ADV are considered. Modern designs of capsules and nanodroplets (NDs) are shown, and the material choices and their implications for function are discussed. The influence of the physical properties of the induced acoustic field, the surrounding medium, and thermophysical effects on the vaporization are presented. Lastly, current challenges and potential future applications towards the implementation of the therapeutic droplets are discussed. Hindawi 2019-07-14 /pmc/articles/PMC6662494/ /pubmed/31392217 http://dx.doi.org/10.1155/2019/9480193 Text en Copyright © 2019 Ksenia Loskutova et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Loskutova, Ksenia Grishenkov, Dmitry Ghorbani, Morteza Review on Acoustic Droplet Vaporization in Ultrasound Diagnostics and Therapeutics |
title | Review on Acoustic Droplet Vaporization in Ultrasound Diagnostics and Therapeutics |
title_full | Review on Acoustic Droplet Vaporization in Ultrasound Diagnostics and Therapeutics |
title_fullStr | Review on Acoustic Droplet Vaporization in Ultrasound Diagnostics and Therapeutics |
title_full_unstemmed | Review on Acoustic Droplet Vaporization in Ultrasound Diagnostics and Therapeutics |
title_short | Review on Acoustic Droplet Vaporization in Ultrasound Diagnostics and Therapeutics |
title_sort | review on acoustic droplet vaporization in ultrasound diagnostics and therapeutics |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662494/ https://www.ncbi.nlm.nih.gov/pubmed/31392217 http://dx.doi.org/10.1155/2019/9480193 |
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