Migration rather than proliferation transcriptomic signatures are strongly associated with breast cancer patient survival

The efficacy of prospective cancer treatments is routinely estimated by in vitro cell-line proliferation screens. However, it is unclear whether tumor aggressiveness and patient survival are influenced more by the proliferative or the migratory properties of cancer cells. To address this question, w...

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Detalles Bibliográficos
Autores principales: Nair, Nishanth Ulhas, Das, Avinash, Rogkoti, Vasiliki-Maria, Fokkelman, Michiel, Marcotte, Richard, de Jong, Chiaro G., Koedoot, Esmee, Lee, Joo Sang, Meilijson, Isaac, Hannenhalli, Sridhar, Neel, Benjamin G., de Water, Bob van, Le Dévédec, Sylvia E., Ruppin, Eytan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662662/
https://www.ncbi.nlm.nih.gov/pubmed/31358840
http://dx.doi.org/10.1038/s41598-019-47440-w

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