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Roles of matricellular CCN2 deposited by osteocytes in osteoclastogenesis and osteoblast differentiation

In this study, we investigated the effect of CCN2 (cellular communication network factor 2), previously termed connective tissue growth factor, deposited in bone matrix on osteoclastogenesis and osteoblast differentiation. To mimic the bone matrix environment, osteocytic MLO-Y4 cells had been embedd...

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Detalles Bibliográficos
Autores principales: Nishida, Takashi, Kubota, Satoshi, Yokoi, Hideki, Mukoyama, Masashi, Takigawa, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662664/
https://www.ncbi.nlm.nih.gov/pubmed/31358778
http://dx.doi.org/10.1038/s41598-019-47285-3