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Roles of matricellular CCN2 deposited by osteocytes in osteoclastogenesis and osteoblast differentiation
In this study, we investigated the effect of CCN2 (cellular communication network factor 2), previously termed connective tissue growth factor, deposited in bone matrix on osteoclastogenesis and osteoblast differentiation. To mimic the bone matrix environment, osteocytic MLO-Y4 cells had been embedd...
Autores principales: | Nishida, Takashi, Kubota, Satoshi, Yokoi, Hideki, Mukoyama, Masashi, Takigawa, Masaharu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662664/ https://www.ncbi.nlm.nih.gov/pubmed/31358778 http://dx.doi.org/10.1038/s41598-019-47285-3 |
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