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Population variability of rhesus macaque (Macaca mulatta) NAT1 gene for arylamine N-acetyltransferase 1: Functional effects and comparison with human

Human NAT1 gene for N-acetyltransferase 1 modulates xenobiotic metabolism of arylamine drugs and mutagens. Beyond pharmacogenetics, NAT1 is also relevant to breast cancer. The population history of human NAT1 suggests evolution through purifying selection, but it is unclear whether this pattern is e...

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Detalles Bibliográficos
Autores principales:	Boukouvala, Sotiria, Chasapopoulou, Zoi, Giannouri, Despina, Kontomina, Evanthia, Marinakis, Nikolaos, Rizou, Sophia V., Stefani, Ioanna, Tsirka, Theodora, Veyssière, Charlotte, Zaliou, Sofia, Sabbagh, Audrey, Crouau-Roy, Brigitte, Fakis, Giannoulis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662693/ https://www.ncbi.nlm.nih.gov/pubmed/31358821 http://dx.doi.org/10.1038/s41598-019-47485-x

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