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Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis
Accumulating evidence illustrates a fundamental role for mitochondria in lung alveolar type 2 epithelial cell (AEC2) dysfunction in the pathogenesis of idiopathic pulmonary fibrosis. However, the role of mitochondrial fusion in AEC2 function and lung fibrosis development remains unknown. Here we rep...
Autores principales: | Chung, Kuei-Pin, Hsu, Chia-Lang, Fan, Li-Chao, Huang, Ziling, Bhatia, Divya, Chen, Yi-Jung, Hisata, Shu, Cho, Soo Jung, Nakahira, Kiichi, Imamura, Mitsuru, Choi, Mary E., Yu, Chong-Jen, Cloonan, Suzanne M., Choi, Augustine M. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662701/ https://www.ncbi.nlm.nih.gov/pubmed/31358769 http://dx.doi.org/10.1038/s41467-019-11327-1 |
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