Short amylin receptor antagonist peptides improve memory deficits in Alzheimer’s disease mouse model

Recent evidence supports involvement of amylin and the amylin receptor in the pathogenesis of Alzheimer’s disease (AD). We have previously shown that amylin receptor antagonist, AC253, improves spatial memory in AD mouse models. Herein, we generated and screened a peptide library and identified two...

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Detalles Bibliográficos
Autores principales: Soudy, Rania, Kimura, Ryoichi, Patel, Aarti, Fu, Wen, Kaur, Kamaljit, Westaway, David, Yang, Jing, Jhamandas, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662706/
https://www.ncbi.nlm.nih.gov/pubmed/31358858
http://dx.doi.org/10.1038/s41598-019-47255-9

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