Hyaluronan abrogates imatinib-induced senescence in chronic myeloid leukemia cell lines

Hyaluronan (HA) is the main glycosaminoglycan of the extracellular matrix. CD44 is the most important HA receptor, and both have been associated with poor prognosis in cancer. Chronic myeloid leukemia (CML) is characterized by the presence of a constitutively activated tyrosine kinase (Breakpoint Cl...

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Detalles Bibliográficos
Autores principales: Lompardía, Silvina, Díaz, Mariángeles, Pibuel, Matías, Papademetrio, Daniela, Poodts, Daniela, Mihalez, Cintia, Álvarez, Élida, Hajos, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662747/
https://www.ncbi.nlm.nih.gov/pubmed/31358779
http://dx.doi.org/10.1038/s41598-019-47248-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662747/
https://www.ncbi.nlm.nih.gov/pubmed/31358779
http://dx.doi.org/10.1038/s41598-019-47248-8

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