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Probing conformational changes of monomeric transthyretin with second derivative fluorescence

We have studied the intrinsic fluorescence spectra of a monomeric variant of human transthyretin (M-TTR), a protein involved in the transport of the thyroid hormone and retinol and associated with various forms of amyloidosis, extending our analysis to the second order derivative of the spectra. Thi...

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Detalles Bibliográficos
Autores principales:	Jazaj, Denisa, Ghadami, Seyyed Abolghasem, Bemporad, Francesco, Chiti, Fabrizio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662758/ https://www.ncbi.nlm.nih.gov/pubmed/31358790 http://dx.doi.org/10.1038/s41598-019-47230-4

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