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Anti-apoptotic effect of the Shh signaling pathway in cigarette smoke extract induced MLE 12 apoptosis

INTRODUCTION: Many studies have shown that COPD is associated with apoptosis of bronchial or alveolar epithelial cells. Alveolar type II epithelial cells (AECII) play an important role in the pathogenetic process. Cigarette smoke extract (CSE) can induce apoptosis of AECII. The Sonic hedgehog (Shh)...

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Detalles Bibliográficos
Autores principales: Li, Jinhua, Zong, Dandan, Chen, Yan, Chen, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Publishing on behalf of the International Society for the Prevention of Tobacco Induced Diseases (ISPTID) 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662799/
https://www.ncbi.nlm.nih.gov/pubmed/31516492
http://dx.doi.org/10.18332/tid/109753