A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity

Autoreactivity to myeloperoxidase (MPO) causes anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), with rapidly progressive glomerulonephritis. Here, we show that a Staphylococcus aureus peptide, homologous to an immunodominant MPO T-cell epitope (MPO(409–428)), can induce anti-...

Descripción completa

Detalles Bibliográficos
Autores principales: Ooi, Joshua D., Jiang, Jhih-Hang, Eggenhuizen, Peter J., Chua, Ling L., van Timmeren, Mirjan, Loh, Khai L., O’Sullivan, Kim M., Gan, Poh Y., Zhong, Yong, Tsyganov, Kirill, Shochet, Lani R., Ryan, Jessica, Stegeman, Coen A., Fugger, Lars, Reid, Hugh H., Rossjohn, Jamie, Heeringa, Peter, Holdsworth, Stephen R., Peleg, Anton Y., Kitching, A. Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662820/
https://www.ncbi.nlm.nih.gov/pubmed/31358739
http://dx.doi.org/10.1038/s41467-019-11255-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662820/
https://www.ncbi.nlm.nih.gov/pubmed/31358739
http://dx.doi.org/10.1038/s41467-019-11255-0

Ejemplares similares