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Polarity signaling ensures epidermal homeostasis by coupling cellular mechanics and genomic integrity

Epithelial homeostasis requires balanced progenitor cell proliferation and differentiation, whereas disrupting this equilibrium fosters degeneration or cancer. Here we studied how cell polarity signaling orchestrates epidermal self-renewal and differentiation. Using genetic ablation, quantitative im...

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Detalles Bibliográficos
Autores principales:	Dias Gomes, Martim, Letzian, Soriba, Saynisch, Michael, Iden, Sandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662827/ https://www.ncbi.nlm.nih.gov/pubmed/31358743 http://dx.doi.org/10.1038/s41467-019-11325-3

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