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Activation of DR3 signaling causes loss of ILC3s and exacerbates intestinal inflammation

TNF-like ligand 1 A (TL1A) and death receptor 3 (DR3) are a ligand-receptor pair involved in the pathogenesis of inflammatory bowel disease. Group 3 innate lymphoid cells (ILC3s) regulate intestinal immunity and highly express DR3. Here, we report that activation of DR3 signaling by an agonistic ant...

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Detalles Bibliográficos
Autores principales:	Li, Jingyu, Shi, Wenli, Sun, Hanxiao, Ji, Yan, Chen, Yuqin, Guo, Xiaohuan, Sheng, Huiming, Shu, Jie, Zhou, Liang, Cai, Ting, Qiu, Ju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662828/ https://www.ncbi.nlm.nih.gov/pubmed/31358760 http://dx.doi.org/10.1038/s41467-019-11304-8

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