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ER-residential Nogo-B accelerates NAFLD-associated HCC mediated by metabolic reprogramming of oxLDL lipophagy
Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome that elevates the risk of hepatocellular carcinoma (HCC). Although alteration of lipid metabolism has been increasingly recognized as a hallmark of cancer cells, the deregulated metabolic modulation of H...
Autores principales: | Tian, Yuan, Yang, Bin, Qiu, Weinan, Hao, Yajing, Zhang, Zhenxing, Yang, Bo, Li, Nan, Cheng, Shuqun, Lin, Zhangjun, Rui, Yao-cheng, Cheung, Otto K. W., Yang, Weiqin, Wu, William K. K., Cheung, Yue-Sun, Lai, Paul B. S., Luo, Jianjun, Sung, Joseph J. Y., Chen, Runsheng, Wang, Hong-Yang, Cheng, Alfred S. L., Yang, Pengyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662851/ https://www.ncbi.nlm.nih.gov/pubmed/31358770 http://dx.doi.org/10.1038/s41467-019-11274-x |
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