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Connection between the heart and the gut

CLINICAL INTRODUCTION: A 45-year-old man with ulcerative colitis was admitted with bloody diarrhoea and chest pain. Inflammatory markers and high-sensitivity troponin were elevated (C reactive protein 57 mg/L, white cell count 10.65×10(9)/L, neutrophil 6.6×10(9)/L, Troponin-I 663 mmol/L). The ECG sh...

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Autores principales: Berlot, Bostjan, Harries, Iwan, Bucciarelli-Ducci, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662949/
https://www.ncbi.nlm.nih.gov/pubmed/30962193
http://dx.doi.org/10.1136/heartjnl-2019-314832
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author Berlot, Bostjan
Harries, Iwan
Bucciarelli-Ducci, Chiara
author_facet Berlot, Bostjan
Harries, Iwan
Bucciarelli-Ducci, Chiara
author_sort Berlot, Bostjan
collection PubMed
description CLINICAL INTRODUCTION: A 45-year-old man with ulcerative colitis was admitted with bloody diarrhoea and chest pain. Inflammatory markers and high-sensitivity troponin were elevated (C reactive protein 57 mg/L, white cell count 10.65×10(9)/L, neutrophil 6.6×10(9)/L, Troponin-I 663 mmol/L). The ECG showed inferior ST-elevation. Urgent coronary angiography revealed unobstructed coronary arteries. Inpatient cardiovascular magnetic resonance (CMR) was arranged to determine the aetiology of the myocardial infarction with non-obstructive coronary arteries. The imaging protocol at 1.5 T included balanced steady-state free precession cine images, T2-weighted oedema sequences, and early and late gadolinium enhancement (LGE). Native T1 and T2 mapping images provided advanced tissue characterisation (figure 1). QUESTION: What is the most likely diagnosis based on the MRI findings?  A. Multiple embolic myocardial infarctions in the right coronary artery territory. B. Acute autoimmune myocarditis. C. Cardiac sarcoidosis. D. Stress (Takotsubo) cardiomyopathy. E. Multiple embolic myocardial infarctions in the left circumflex coronary artery territory.
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spelling pubmed-66629492019-08-12 Connection between the heart and the gut Berlot, Bostjan Harries, Iwan Bucciarelli-Ducci, Chiara Heart Image Challenge CLINICAL INTRODUCTION: A 45-year-old man with ulcerative colitis was admitted with bloody diarrhoea and chest pain. Inflammatory markers and high-sensitivity troponin were elevated (C reactive protein 57 mg/L, white cell count 10.65×10(9)/L, neutrophil 6.6×10(9)/L, Troponin-I 663 mmol/L). The ECG showed inferior ST-elevation. Urgent coronary angiography revealed unobstructed coronary arteries. Inpatient cardiovascular magnetic resonance (CMR) was arranged to determine the aetiology of the myocardial infarction with non-obstructive coronary arteries. The imaging protocol at 1.5 T included balanced steady-state free precession cine images, T2-weighted oedema sequences, and early and late gadolinium enhancement (LGE). Native T1 and T2 mapping images provided advanced tissue characterisation (figure 1). QUESTION: What is the most likely diagnosis based on the MRI findings?  A. Multiple embolic myocardial infarctions in the right coronary artery territory. B. Acute autoimmune myocarditis. C. Cardiac sarcoidosis. D. Stress (Takotsubo) cardiomyopathy. E. Multiple embolic myocardial infarctions in the left circumflex coronary artery territory. BMJ Publishing Group 2019-08 2019-04-08 /pmc/articles/PMC6662949/ /pubmed/30962193 http://dx.doi.org/10.1136/heartjnl-2019-314832 Text en © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Image Challenge
Berlot, Bostjan
Harries, Iwan
Bucciarelli-Ducci, Chiara
Connection between the heart and the gut
title Connection between the heart and the gut
title_full Connection between the heart and the gut
title_fullStr Connection between the heart and the gut
title_full_unstemmed Connection between the heart and the gut
title_short Connection between the heart and the gut
title_sort connection between the heart and the gut
topic Image Challenge
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662949/
https://www.ncbi.nlm.nih.gov/pubmed/30962193
http://dx.doi.org/10.1136/heartjnl-2019-314832
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