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Longevity is determined by ETS transcription factors in multiple tissues and diverse species

Ageing populations pose one of the main public health crises of our time. Reprogramming gene expression by altering the activities of sequence-specific transcription factors (TFs) can ameliorate deleterious effects of age. Here we explore how a circuit of TFs coordinates pro-longevity transcriptiona...

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Detalles Bibliográficos
Autores principales: Dobson, Adam J., Boulton-McDonald, Richard, Houchou, Lara, Svermova, Tatiana, Ren, Ziyu, Subrini, Jeremie, Vazquez-Prada, Mireya, Hoti, Mimoza, Rodriguez-Lopez, Maria, Ibrahim, Rita, Gregoriou, Afroditi, Gkantiragas, Alexis, Bähler, Jürg, Ezcurra, Marina, Alic, Nazif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662994/
https://www.ncbi.nlm.nih.gov/pubmed/31356597
http://dx.doi.org/10.1371/journal.pgen.1008212

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