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Longevity is determined by ETS transcription factors in multiple tissues and diverse species
Ageing populations pose one of the main public health crises of our time. Reprogramming gene expression by altering the activities of sequence-specific transcription factors (TFs) can ameliorate deleterious effects of age. Here we explore how a circuit of TFs coordinates pro-longevity transcriptiona...
Autores principales: | Dobson, Adam J., Boulton-McDonald, Richard, Houchou, Lara, Svermova, Tatiana, Ren, Ziyu, Subrini, Jeremie, Vazquez-Prada, Mireya, Hoti, Mimoza, Rodriguez-Lopez, Maria, Ibrahim, Rita, Gregoriou, Afroditi, Gkantiragas, Alexis, Bähler, Jürg, Ezcurra, Marina, Alic, Nazif |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662994/ https://www.ncbi.nlm.nih.gov/pubmed/31356597 http://dx.doi.org/10.1371/journal.pgen.1008212 |
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