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Mode of action of the antimicrobial peptide Mel4 is independent of Staphylococcus aureus cell membrane permeability

Mel4 is a novel cationic peptide with potent activity against Gram-positive bacteria. The current study examined the anti-staphylococcal mechanism of action of Mel4 and its precursor peptide melimine. The interaction of peptides with lipoteichoic acid (LTA) and with the cytoplasmic membrane using Di...

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Detalles Bibliográficos
Autores principales: Yasir, Muhammad, Dutta, Debarun, Willcox, Mark D. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663011/
https://www.ncbi.nlm.nih.gov/pubmed/31356627
http://dx.doi.org/10.1371/journal.pone.0215703

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