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Factors Associated with Complicated Appendicitis: View from a Low-middle Income Country
Introduction Factors associated with complicated appendicitis have been inconsistently identified. Moreover, studies are lacking from low and low-middle countries where access to surgical care is limited. Our objective was to identify factors predicting complicated appendicitis as diagnosed intraope...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663039/ https://www.ncbi.nlm.nih.gov/pubmed/31363446 http://dx.doi.org/10.7759/cureus.4765 |
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author | Khan, Muhammad Sohaib Siddiqui, Muhammad Tayyab H Shahzad, Noman Haider, Aleezay Chaudhry, Mustafa Belal Hafeez Alvi, Rehman |
author_facet | Khan, Muhammad Sohaib Siddiqui, Muhammad Tayyab H Shahzad, Noman Haider, Aleezay Chaudhry, Mustafa Belal Hafeez Alvi, Rehman |
author_sort | Khan, Muhammad Sohaib |
collection | PubMed |
description | Introduction Factors associated with complicated appendicitis have been inconsistently identified. Moreover, studies are lacking from low and low-middle countries where access to surgical care is limited. Our objective was to identify factors predicting complicated appendicitis as diagnosed intraoperatively in a low-middle income country hospital. Methodology Retrospective case-control study of patients who underwent laparoscopic appendectomy from 01/2008 to 12/2015 was completed. Based on intraoperative diagnosis of complicated appendicitis, patients were divided into two groups; those with complicated appendicitis (CA) and those who had non-complicated appendicitis (NCA). CT scans were further reviewed to identify presence of appendicolith. Result Of the 442 patients included, 88 (20%) patients were in the CA group while 354 (80%) patients were in the NCA group. Patients in the CA group were older [CA vs. NCA: 34.6 ± 14 vs. 30.4 ± 11.5; p-value < 0.001], had symptoms for longer duration [CA vs. NCA: 2 ± 1.2 vs. 1.5 ± 0.8; p-value: 0.001] and had a greater proportion of patients with appendicoliths [CA vs. NCA: 37 (42%) vs. 84 (23.7%); p-value: 0.001]. On multivariable regression analysis, patients with complicated appendicitis had greater odds of having appendicoliths (OR: 2.4, 95% CI: 1.4-4.07; p-value < 0.001) and symptoms for a longer duration (OR: 1.57, 95% CI: 1.25-1.97; p-value < 0.001). Conclusion Patients with complicated appendicitis had greater odds of having appendicoliths and symptoms for a longer duration. Further studies are warranted in low and low-middle income countries to gauge the impact delay in presentation and intervention has on appendicitis and its outcomes. |
format | Online Article Text |
id | pubmed-6663039 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-66630392019-07-30 Factors Associated with Complicated Appendicitis: View from a Low-middle Income Country Khan, Muhammad Sohaib Siddiqui, Muhammad Tayyab H Shahzad, Noman Haider, Aleezay Chaudhry, Mustafa Belal Hafeez Alvi, Rehman Cureus General Surgery Introduction Factors associated with complicated appendicitis have been inconsistently identified. Moreover, studies are lacking from low and low-middle countries where access to surgical care is limited. Our objective was to identify factors predicting complicated appendicitis as diagnosed intraoperatively in a low-middle income country hospital. Methodology Retrospective case-control study of patients who underwent laparoscopic appendectomy from 01/2008 to 12/2015 was completed. Based on intraoperative diagnosis of complicated appendicitis, patients were divided into two groups; those with complicated appendicitis (CA) and those who had non-complicated appendicitis (NCA). CT scans were further reviewed to identify presence of appendicolith. Result Of the 442 patients included, 88 (20%) patients were in the CA group while 354 (80%) patients were in the NCA group. Patients in the CA group were older [CA vs. NCA: 34.6 ± 14 vs. 30.4 ± 11.5; p-value < 0.001], had symptoms for longer duration [CA vs. NCA: 2 ± 1.2 vs. 1.5 ± 0.8; p-value: 0.001] and had a greater proportion of patients with appendicoliths [CA vs. NCA: 37 (42%) vs. 84 (23.7%); p-value: 0.001]. On multivariable regression analysis, patients with complicated appendicitis had greater odds of having appendicoliths (OR: 2.4, 95% CI: 1.4-4.07; p-value < 0.001) and symptoms for a longer duration (OR: 1.57, 95% CI: 1.25-1.97; p-value < 0.001). Conclusion Patients with complicated appendicitis had greater odds of having appendicoliths and symptoms for a longer duration. Further studies are warranted in low and low-middle income countries to gauge the impact delay in presentation and intervention has on appendicitis and its outcomes. Cureus 2019-05-28 /pmc/articles/PMC6663039/ /pubmed/31363446 http://dx.doi.org/10.7759/cureus.4765 Text en Copyright © 2019, Khan et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | General Surgery Khan, Muhammad Sohaib Siddiqui, Muhammad Tayyab H Shahzad, Noman Haider, Aleezay Chaudhry, Mustafa Belal Hafeez Alvi, Rehman Factors Associated with Complicated Appendicitis: View from a Low-middle Income Country |
title | Factors Associated with Complicated Appendicitis: View from a Low-middle Income Country |
title_full | Factors Associated with Complicated Appendicitis: View from a Low-middle Income Country |
title_fullStr | Factors Associated with Complicated Appendicitis: View from a Low-middle Income Country |
title_full_unstemmed | Factors Associated with Complicated Appendicitis: View from a Low-middle Income Country |
title_short | Factors Associated with Complicated Appendicitis: View from a Low-middle Income Country |
title_sort | factors associated with complicated appendicitis: view from a low-middle income country |
topic | General Surgery |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663039/ https://www.ncbi.nlm.nih.gov/pubmed/31363446 http://dx.doi.org/10.7759/cureus.4765 |
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