Cargando…
Multiple Myeloma in an Agricultural Worker Exposed to Pesticides
Multiple myeloma (MM) is a neoplastic disorder characterized by the monoclonal proliferation of plasma cells in the bone marrow. It is estimated to account for only 1% of neoplastic diseases, and there is still a great deal of uncertainty about its precise etiology. Common risk factors with a proven...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663119/ https://www.ncbi.nlm.nih.gov/pubmed/31363443 http://dx.doi.org/10.7759/cureus.4762 |
_version_ | 1783439768526258176 |
---|---|
author | Packard, Elizabeth Shahid, Zainab Groff, Andrew Patel, Ravi Jain, Rohit |
author_facet | Packard, Elizabeth Shahid, Zainab Groff, Andrew Patel, Ravi Jain, Rohit |
author_sort | Packard, Elizabeth |
collection | PubMed |
description | Multiple myeloma (MM) is a neoplastic disorder characterized by the monoclonal proliferation of plasma cells in the bone marrow. It is estimated to account for only 1% of neoplastic diseases, and there is still a great deal of uncertainty about its precise etiology. Common risk factors with a proven association with MM include ionizing radiation exposure, age greater than 65, male gender, and the presence of monoclonal gammopathy of unknown significance (MGUS).More recently, research has shown that occupational exposures to pesticides also have a significant association with the development of MM. We present the case of an adult male who presented with rib pain, back pain, fevers, and progressive shortness of breath and was ultimately found to have multiple myeloma thought to be associated with occupational exposure to the pesticide captan. |
format | Online Article Text |
id | pubmed-6663119 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-66631192019-07-30 Multiple Myeloma in an Agricultural Worker Exposed to Pesticides Packard, Elizabeth Shahid, Zainab Groff, Andrew Patel, Ravi Jain, Rohit Cureus Internal Medicine Multiple myeloma (MM) is a neoplastic disorder characterized by the monoclonal proliferation of plasma cells in the bone marrow. It is estimated to account for only 1% of neoplastic diseases, and there is still a great deal of uncertainty about its precise etiology. Common risk factors with a proven association with MM include ionizing radiation exposure, age greater than 65, male gender, and the presence of monoclonal gammopathy of unknown significance (MGUS).More recently, research has shown that occupational exposures to pesticides also have a significant association with the development of MM. We present the case of an adult male who presented with rib pain, back pain, fevers, and progressive shortness of breath and was ultimately found to have multiple myeloma thought to be associated with occupational exposure to the pesticide captan. Cureus 2019-05-28 /pmc/articles/PMC6663119/ /pubmed/31363443 http://dx.doi.org/10.7759/cureus.4762 Text en Copyright © 2019, Packard et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Packard, Elizabeth Shahid, Zainab Groff, Andrew Patel, Ravi Jain, Rohit Multiple Myeloma in an Agricultural Worker Exposed to Pesticides |
title | Multiple Myeloma in an Agricultural Worker Exposed to Pesticides |
title_full | Multiple Myeloma in an Agricultural Worker Exposed to Pesticides |
title_fullStr | Multiple Myeloma in an Agricultural Worker Exposed to Pesticides |
title_full_unstemmed | Multiple Myeloma in an Agricultural Worker Exposed to Pesticides |
title_short | Multiple Myeloma in an Agricultural Worker Exposed to Pesticides |
title_sort | multiple myeloma in an agricultural worker exposed to pesticides |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663119/ https://www.ncbi.nlm.nih.gov/pubmed/31363443 http://dx.doi.org/10.7759/cureus.4762 |
work_keys_str_mv | AT packardelizabeth multiplemyelomainanagriculturalworkerexposedtopesticides AT shahidzainab multiplemyelomainanagriculturalworkerexposedtopesticides AT groffandrew multiplemyelomainanagriculturalworkerexposedtopesticides AT patelravi multiplemyelomainanagriculturalworkerexposedtopesticides AT jainrohit multiplemyelomainanagriculturalworkerexposedtopesticides |