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Multiple Myeloma in an Agricultural Worker Exposed to Pesticides

Multiple myeloma (MM) is a neoplastic disorder characterized by the monoclonal proliferation of plasma cells in the bone marrow. It is estimated to account for only 1% of neoplastic diseases, and there is still a great deal of uncertainty about its precise etiology. Common risk factors with a proven...

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Autores principales: Packard, Elizabeth, Shahid, Zainab, Groff, Andrew, Patel, Ravi, Jain, Rohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663119/
https://www.ncbi.nlm.nih.gov/pubmed/31363443
http://dx.doi.org/10.7759/cureus.4762
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author Packard, Elizabeth
Shahid, Zainab
Groff, Andrew
Patel, Ravi
Jain, Rohit
author_facet Packard, Elizabeth
Shahid, Zainab
Groff, Andrew
Patel, Ravi
Jain, Rohit
author_sort Packard, Elizabeth
collection PubMed
description Multiple myeloma (MM) is a neoplastic disorder characterized by the monoclonal proliferation of plasma cells in the bone marrow. It is estimated to account for only 1% of neoplastic diseases, and there is still a great deal of uncertainty about its precise etiology. Common risk factors with a proven association with MM include ionizing radiation exposure, age greater than 65, male gender, and the presence of monoclonal gammopathy of unknown significance (MGUS).More recently, research has shown that occupational exposures to pesticides also have a significant association with the development of MM. We present the case of an adult male who presented with rib pain, back pain, fevers, and progressive shortness of breath and was ultimately found to have multiple myeloma thought to be associated with occupational exposure to the pesticide captan.
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spelling pubmed-66631192019-07-30 Multiple Myeloma in an Agricultural Worker Exposed to Pesticides Packard, Elizabeth Shahid, Zainab Groff, Andrew Patel, Ravi Jain, Rohit Cureus Internal Medicine Multiple myeloma (MM) is a neoplastic disorder characterized by the monoclonal proliferation of plasma cells in the bone marrow. It is estimated to account for only 1% of neoplastic diseases, and there is still a great deal of uncertainty about its precise etiology. Common risk factors with a proven association with MM include ionizing radiation exposure, age greater than 65, male gender, and the presence of monoclonal gammopathy of unknown significance (MGUS).More recently, research has shown that occupational exposures to pesticides also have a significant association with the development of MM. We present the case of an adult male who presented with rib pain, back pain, fevers, and progressive shortness of breath and was ultimately found to have multiple myeloma thought to be associated with occupational exposure to the pesticide captan. Cureus 2019-05-28 /pmc/articles/PMC6663119/ /pubmed/31363443 http://dx.doi.org/10.7759/cureus.4762 Text en Copyright © 2019, Packard et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Packard, Elizabeth
Shahid, Zainab
Groff, Andrew
Patel, Ravi
Jain, Rohit
Multiple Myeloma in an Agricultural Worker Exposed to Pesticides
title Multiple Myeloma in an Agricultural Worker Exposed to Pesticides
title_full Multiple Myeloma in an Agricultural Worker Exposed to Pesticides
title_fullStr Multiple Myeloma in an Agricultural Worker Exposed to Pesticides
title_full_unstemmed Multiple Myeloma in an Agricultural Worker Exposed to Pesticides
title_short Multiple Myeloma in an Agricultural Worker Exposed to Pesticides
title_sort multiple myeloma in an agricultural worker exposed to pesticides
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663119/
https://www.ncbi.nlm.nih.gov/pubmed/31363443
http://dx.doi.org/10.7759/cureus.4762
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