Cargando…

Topological gene expression networks recapitulate brain anatomy and function

Understanding how gene expression translates to and affects human behavior is one of the ultimate goals of neuroscience. In this paper, we present a pipeline based on Mapper, a topological simplification tool, to analyze gene co-expression data. We first validate the method by reproducing key result...

Descripción completa

Detalles Bibliográficos
Autores principales: Patania, Alice, Selvaggi, Pierluigi, Veronese, Mattia, Dipasquale, Ottavia, Expert, Paul, Petri, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MIT Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663211/
https://www.ncbi.nlm.nih.gov/pubmed/31410377
http://dx.doi.org/10.1162/netn_a_00094