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Laparoscopic Heller Myotomy for Achalasia: Experience from a Single Referral Tertiary Center

BACKGROUND Achalasia is the most well known esophageal motility disorder. Laparoscopic Heller myotomy (LHM) is the most effective treatment for achalasia. The aim of this study was to review our results on LHM for achalasia. METHODS In this cross-sectional study all patients undergoing LHM between 2...

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Autores principales: Mirsharifi, Alireza, Ghorbani Abdehgah, Ali, Mirsharifi, Rasoul, Jafari, Mehdi, Fattah, Noor, Mikaeli, Javad, Soroush, Ahmad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Association of Gastroerterology and Hepatology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663286/
https://www.ncbi.nlm.nih.gov/pubmed/31380005
http://dx.doi.org/10.15171/mejdd.2018.133
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author Mirsharifi, Alireza
Ghorbani Abdehgah, Ali
Mirsharifi, Rasoul
Jafari, Mehdi
Fattah, Noor
Mikaeli, Javad
Soroush, Ahmad Reza
author_facet Mirsharifi, Alireza
Ghorbani Abdehgah, Ali
Mirsharifi, Rasoul
Jafari, Mehdi
Fattah, Noor
Mikaeli, Javad
Soroush, Ahmad Reza
author_sort Mirsharifi, Alireza
collection PubMed
description BACKGROUND Achalasia is the most well known esophageal motility disorder. Laparoscopic Heller myotomy (LHM) is the most effective treatment for achalasia. The aim of this study was to review our results on LHM for achalasia. METHODS In this cross-sectional study all patients undergoing LHM between 2015 and 2017 were studied. The myotomy was followed by an anterior or posterior partial fundoplication. All patients were followed up for at least six months. RESULTS We conducted this prospective study on 36 consecutive patients who underwent LHM over 3 years. The mean age of the patients was 36.64 ± 13.47 years. 30 patients (83.3%) underwent Toupet and 6 patients (16.7%) received Dor fundoplication. 11 patients (30.6%) developed reflux after the procedure. According to the Eckardt Symptom Scoring (ESS), the symptoms improved in 74.2% of the patients and remained unchanged in 25.8% of the patients. Analysis of the ESS, indicated a significant change in regurgitation and retrosternal pain, dysphagia, and weight loss after the surgery (p = 0.001, p = 0.002, p = 0.046, and p = 0.001, respectively). CONCLUSION LHM with anterior or posterior partial fundoplication is safe and achieves a good outcome in the treatment of achalasia, especially in patients who have not responded to other methods while no serious complication was reported despite several prior endoscopic interventions.
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spelling pubmed-66632862019-08-02 Laparoscopic Heller Myotomy for Achalasia: Experience from a Single Referral Tertiary Center Mirsharifi, Alireza Ghorbani Abdehgah, Ali Mirsharifi, Rasoul Jafari, Mehdi Fattah, Noor Mikaeli, Javad Soroush, Ahmad Reza Middle East J Dig Dis Original Article BACKGROUND Achalasia is the most well known esophageal motility disorder. Laparoscopic Heller myotomy (LHM) is the most effective treatment for achalasia. The aim of this study was to review our results on LHM for achalasia. METHODS In this cross-sectional study all patients undergoing LHM between 2015 and 2017 were studied. The myotomy was followed by an anterior or posterior partial fundoplication. All patients were followed up for at least six months. RESULTS We conducted this prospective study on 36 consecutive patients who underwent LHM over 3 years. The mean age of the patients was 36.64 ± 13.47 years. 30 patients (83.3%) underwent Toupet and 6 patients (16.7%) received Dor fundoplication. 11 patients (30.6%) developed reflux after the procedure. According to the Eckardt Symptom Scoring (ESS), the symptoms improved in 74.2% of the patients and remained unchanged in 25.8% of the patients. Analysis of the ESS, indicated a significant change in regurgitation and retrosternal pain, dysphagia, and weight loss after the surgery (p = 0.001, p = 0.002, p = 0.046, and p = 0.001, respectively). CONCLUSION LHM with anterior or posterior partial fundoplication is safe and achieves a good outcome in the treatment of achalasia, especially in patients who have not responded to other methods while no serious complication was reported despite several prior endoscopic interventions. Iranian Association of Gastroerterology and Hepatology 2019-04 2019-01-25 /pmc/articles/PMC6663286/ /pubmed/31380005 http://dx.doi.org/10.15171/mejdd.2018.133 Text en © 2019 The Author(s) This work is published by Middle East Journal of Digestive Diseaes as an open access article distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.
spellingShingle Original Article
Mirsharifi, Alireza
Ghorbani Abdehgah, Ali
Mirsharifi, Rasoul
Jafari, Mehdi
Fattah, Noor
Mikaeli, Javad
Soroush, Ahmad Reza
Laparoscopic Heller Myotomy for Achalasia: Experience from a Single Referral Tertiary Center
title Laparoscopic Heller Myotomy for Achalasia: Experience from a Single Referral Tertiary Center
title_full Laparoscopic Heller Myotomy for Achalasia: Experience from a Single Referral Tertiary Center
title_fullStr Laparoscopic Heller Myotomy for Achalasia: Experience from a Single Referral Tertiary Center
title_full_unstemmed Laparoscopic Heller Myotomy for Achalasia: Experience from a Single Referral Tertiary Center
title_short Laparoscopic Heller Myotomy for Achalasia: Experience from a Single Referral Tertiary Center
title_sort laparoscopic heller myotomy for achalasia: experience from a single referral tertiary center
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663286/
https://www.ncbi.nlm.nih.gov/pubmed/31380005
http://dx.doi.org/10.15171/mejdd.2018.133
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