The role of gut microbiota in non-alcoholic fatty liver disease: pathways of mechanisms

Nonalcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome. Its prevalence increases with increasing rates of obesity, insulin resistance, and diabetes mellitus. The pathogenesis of NAFLD involves many factors, including the gastrointestinal microbiota. However, there...

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Detalles Bibliográficos
Autores principales: JASIRWAN, Chyntia Olivia Maurine, LESMANA, Cosmas Rinaldi Adithya, HASAN, Irsan, SULAIMAN, Andri Sanityosos, GANI, Rino Alvani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMFH Press 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663510/
https://www.ncbi.nlm.nih.gov/pubmed/31384519
http://dx.doi.org/10.12938/bmfh.18-032
Descripción
Sumario:Nonalcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome. Its prevalence increases with increasing rates of obesity, insulin resistance, and diabetes mellitus. The pathogenesis of NAFLD involves many factors, including the gastrointestinal microbiota. However, there is still debate about the impact of gut dysbiosis in the NAFLD disease progression. Therefore, this paper aims to review the relationship between gut microbiota and other risk factors for NAFLD and how gut dysbiosis plays a role in the pathogenesis of NAFLD. Hopefully, this paper can make an appropriate contribution to the development of NAFLD research in the future.

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