The role of gut microbiota in non-alcoholic fatty liver disease: pathways of mechanisms

Nonalcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome. Its prevalence increases with increasing rates of obesity, insulin resistance, and diabetes mellitus. The pathogenesis of NAFLD involves many factors, including the gastrointestinal microbiota. However, there...

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Autores principales: JASIRWAN, Chyntia Olivia Maurine, LESMANA, Cosmas Rinaldi Adithya, HASAN, Irsan, SULAIMAN, Andri Sanityosos, GANI, Rino Alvani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMFH Press 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663510/
https://www.ncbi.nlm.nih.gov/pubmed/31384519
http://dx.doi.org/10.12938/bmfh.18-032
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author JASIRWAN, Chyntia Olivia Maurine
LESMANA, Cosmas Rinaldi Adithya
HASAN, Irsan
SULAIMAN, Andri Sanityosos
GANI, Rino Alvani
author_facet JASIRWAN, Chyntia Olivia Maurine
LESMANA, Cosmas Rinaldi Adithya
HASAN, Irsan
SULAIMAN, Andri Sanityosos
GANI, Rino Alvani
author_sort JASIRWAN, Chyntia Olivia Maurine
collection PubMed
description Nonalcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome. Its prevalence increases with increasing rates of obesity, insulin resistance, and diabetes mellitus. The pathogenesis of NAFLD involves many factors, including the gastrointestinal microbiota. However, there is still debate about the impact of gut dysbiosis in the NAFLD disease progression. Therefore, this paper aims to review the relationship between gut microbiota and other risk factors for NAFLD and how gut dysbiosis plays a role in the pathogenesis of NAFLD. Hopefully, this paper can make an appropriate contribution to the development of NAFLD research in the future.
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spelling pubmed-66635102019-08-05 The role of gut microbiota in non-alcoholic fatty liver disease: pathways of mechanisms JASIRWAN, Chyntia Olivia Maurine LESMANA, Cosmas Rinaldi Adithya HASAN, Irsan SULAIMAN, Andri Sanityosos GANI, Rino Alvani Biosci Microbiota Food Health Review Nonalcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome. Its prevalence increases with increasing rates of obesity, insulin resistance, and diabetes mellitus. The pathogenesis of NAFLD involves many factors, including the gastrointestinal microbiota. However, there is still debate about the impact of gut dysbiosis in the NAFLD disease progression. Therefore, this paper aims to review the relationship between gut microbiota and other risk factors for NAFLD and how gut dysbiosis plays a role in the pathogenesis of NAFLD. Hopefully, this paper can make an appropriate contribution to the development of NAFLD research in the future. BMFH Press 2019-05-08 2019 /pmc/articles/PMC6663510/ /pubmed/31384519 http://dx.doi.org/10.12938/bmfh.18-032 Text en ©2019 BMFH Press This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Review
JASIRWAN, Chyntia Olivia Maurine
LESMANA, Cosmas Rinaldi Adithya
HASAN, Irsan
SULAIMAN, Andri Sanityosos
GANI, Rino Alvani
The role of gut microbiota in non-alcoholic fatty liver disease: pathways of mechanisms
title The role of gut microbiota in non-alcoholic fatty liver disease: pathways of mechanisms
title_full The role of gut microbiota in non-alcoholic fatty liver disease: pathways of mechanisms
title_fullStr The role of gut microbiota in non-alcoholic fatty liver disease: pathways of mechanisms
title_full_unstemmed The role of gut microbiota in non-alcoholic fatty liver disease: pathways of mechanisms
title_short The role of gut microbiota in non-alcoholic fatty liver disease: pathways of mechanisms
title_sort role of gut microbiota in non-alcoholic fatty liver disease: pathways of mechanisms
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663510/
https://www.ncbi.nlm.nih.gov/pubmed/31384519
http://dx.doi.org/10.12938/bmfh.18-032
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