Combination of Renal Angioplasty and Angiotensin-converting-enzyme Inhibitor Can Reduce Proteinuria in Patients with Bilateral Renal Artery Disease

Recent large clinical trials failed to show clear benefits of percutaneous transluminal renal angioplasty (PTRA) as compared with medical therapy on patients with renal artery stenosis. It was also reported that proteinuria is an adverse prognostic factor after PTRA, and PTRA is less effective in pa...

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Autores principales: Toda, Hironobu, A. Uchida, Haruhito, Nakamura, Kazufumi, Takeuchi, Hidemi, Kinomura, Masaru, Nakagawa, Koji, Watanabe, Atsuyuki, Miyoshi, Toru, Nishii, Nobuhiro, Morita, Hiroshi, Wada, Jun, Ito, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663532/
https://www.ncbi.nlm.nih.gov/pubmed/30799351
http://dx.doi.org/10.2169/internalmedicine.2076-18
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author Toda, Hironobu
A. Uchida, Haruhito
Nakamura, Kazufumi
Takeuchi, Hidemi
Kinomura, Masaru
Nakagawa, Koji
Watanabe, Atsuyuki
Miyoshi, Toru
Nishii, Nobuhiro
Morita, Hiroshi
Wada, Jun
Ito, Hiroshi
author_facet Toda, Hironobu
A. Uchida, Haruhito
Nakamura, Kazufumi
Takeuchi, Hidemi
Kinomura, Masaru
Nakagawa, Koji
Watanabe, Atsuyuki
Miyoshi, Toru
Nishii, Nobuhiro
Morita, Hiroshi
Wada, Jun
Ito, Hiroshi
author_sort Toda, Hironobu
collection PubMed
description Recent large clinical trials failed to show clear benefits of percutaneous transluminal renal angioplasty (PTRA) as compared with medical therapy on patients with renal artery stenosis. It was also reported that proteinuria is an adverse prognostic factor after PTRA, and PTRA is less effective in patients with overt proteinuria. From the renoprotective point of view, to reduce proteinuria after PTRA is an important therapeutic goal in patients with renal artery stenosis with overt proteinuria. We hereby describe two patients successfully treated by combination therapy with PTRA and administration of angiotensin-converting enzyme (ACE) inhibitor for bilateral renal artery disease with overt proteinuria.
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spelling pubmed-66635322019-07-29 Combination of Renal Angioplasty and Angiotensin-converting-enzyme Inhibitor Can Reduce Proteinuria in Patients with Bilateral Renal Artery Disease Toda, Hironobu A. Uchida, Haruhito Nakamura, Kazufumi Takeuchi, Hidemi Kinomura, Masaru Nakagawa, Koji Watanabe, Atsuyuki Miyoshi, Toru Nishii, Nobuhiro Morita, Hiroshi Wada, Jun Ito, Hiroshi Intern Med Case Report Recent large clinical trials failed to show clear benefits of percutaneous transluminal renal angioplasty (PTRA) as compared with medical therapy on patients with renal artery stenosis. It was also reported that proteinuria is an adverse prognostic factor after PTRA, and PTRA is less effective in patients with overt proteinuria. From the renoprotective point of view, to reduce proteinuria after PTRA is an important therapeutic goal in patients with renal artery stenosis with overt proteinuria. We hereby describe two patients successfully treated by combination therapy with PTRA and administration of angiotensin-converting enzyme (ACE) inhibitor for bilateral renal artery disease with overt proteinuria. The Japanese Society of Internal Medicine 2019-02-25 2019-07-01 /pmc/articles/PMC6663532/ /pubmed/30799351 http://dx.doi.org/10.2169/internalmedicine.2076-18 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Toda, Hironobu
A. Uchida, Haruhito
Nakamura, Kazufumi
Takeuchi, Hidemi
Kinomura, Masaru
Nakagawa, Koji
Watanabe, Atsuyuki
Miyoshi, Toru
Nishii, Nobuhiro
Morita, Hiroshi
Wada, Jun
Ito, Hiroshi
Combination of Renal Angioplasty and Angiotensin-converting-enzyme Inhibitor Can Reduce Proteinuria in Patients with Bilateral Renal Artery Disease
title Combination of Renal Angioplasty and Angiotensin-converting-enzyme Inhibitor Can Reduce Proteinuria in Patients with Bilateral Renal Artery Disease
title_full Combination of Renal Angioplasty and Angiotensin-converting-enzyme Inhibitor Can Reduce Proteinuria in Patients with Bilateral Renal Artery Disease
title_fullStr Combination of Renal Angioplasty and Angiotensin-converting-enzyme Inhibitor Can Reduce Proteinuria in Patients with Bilateral Renal Artery Disease
title_full_unstemmed Combination of Renal Angioplasty and Angiotensin-converting-enzyme Inhibitor Can Reduce Proteinuria in Patients with Bilateral Renal Artery Disease
title_short Combination of Renal Angioplasty and Angiotensin-converting-enzyme Inhibitor Can Reduce Proteinuria in Patients with Bilateral Renal Artery Disease
title_sort combination of renal angioplasty and angiotensin-converting-enzyme inhibitor can reduce proteinuria in patients with bilateral renal artery disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663532/
https://www.ncbi.nlm.nih.gov/pubmed/30799351
http://dx.doi.org/10.2169/internalmedicine.2076-18
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