Characterization and Clinical Significance of Natural Variability in Hepatitis B Virus Reverse Transcriptase in Treatment-Naive Chinese Patients by Sanger Sequencing and Next-Generation Sequencing

Mutations in hepatitis B virus (HBV) reverse transcriptase (RT) are associated with nucleos(t)ide analogue (NA) resistance during long-term antiviral treatment. However, the characterization of mutations in HBV RT in untreated patients has not yet been well illustrated. The objective of this study w...

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Detalles Bibliográficos
Autores principales: Fu, Ya, Zeng, Yongbin, Chen, Tianbin, Chen, Huijuan, Lin, Ni, Lin, Jinpiao, Liu, Xiaofeng, Huang, Er, Wu, Songhang, Wu, Shu, Xu, Siyi, Wang, Long, Ou, Qishui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Virology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663897/
https://www.ncbi.nlm.nih.gov/pubmed/31189581
http://dx.doi.org/10.1128/JCM.00119-19

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