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Receptor for Advanced Glycation End Products Antagonism Blunts Kidney Damage in Transgenic Townes Sickle Mice

A large proportion of adult patients with sickle cell disease (SCD) develops kidney disease and is at a high risk of mortality. The contribution of advanced glycation end products and their receptor (AGE/RAGE) axis has been established in the pathogenesis of multiple kidney diseases. The aim of the...

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Detalles Bibliográficos
Autores principales: Charrin, Emmanuelle, Faes, Camille, Sotiaux, Amandine, Skinner, Sarah, Pialoux, Vincent, Joly, Philippe, Connes, Philippe, Martin, Cyril
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663971/
https://www.ncbi.nlm.nih.gov/pubmed/31396093
http://dx.doi.org/10.3389/fphys.2019.00880