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Developmental Regulation of KCC2 Phosphorylation Has Long-Term Impacts on Cognitive Function

GABA(A) receptor-mediated currents shift from excitatory to inhibitory during postnatal brain development in rodents. A postnatal increase in KCC2 protein expression is considered to be the sole mechanism controlling the developmental onset of hyperpolarizing synaptic transmission, but here we ident...

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Detalles Bibliográficos
Autores principales:	Moore, Yvonne E., Conway, Leslie C., Wobst, Heike J., Brandon, Nicholas J., Deeb, Tarek Z., Moss, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664008/ https://www.ncbi.nlm.nih.gov/pubmed/31396048 http://dx.doi.org/10.3389/fnmol.2019.00173

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