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Multifunctional polymeric micelle-based chemo-immunotherapy with immune checkpoint blockade for efficient treatment of orthotopic and metastatic breast cancer

Immunotherapy has become a highly promising paradigm for cancer treatment. Herein, a chemo-immunotherapy was developed by encapsulating chemotherapeutic drug doxorubicin (DOX) and Toll-like receptor 7 agonist imiquimod (IMQ) in low molecular weight heparin (LMWH)-d-α-tocopheryl succinate (TOS) micel...

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Detalles Bibliográficos
Autores principales:	Wei, Jiaojie, Long, Yang, Guo, Rong, Liu, Xinlei, Tang, Xian, Rao, Jingdong, Yin, Sheng, Zhang, Zhirong, Li, Man, He, Qin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664045/ https://www.ncbi.nlm.nih.gov/pubmed/31384541 http://dx.doi.org/10.1016/j.apsb.2019.01.018

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