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Matrine attenuates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via maintaining AMPKα/UCP2 pathway

Oxidative stress and cardiomyocyte apoptosis are involved in the pathogenesis of doxorubicin (DOX)-induced cardiotoxicity. Matrine is well-known for its powerful anti-oxidant and anti-apoptotic capacities. Our present study aimed to investigate the effect of matrine on DOX-induced cardiotoxicity and...

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Detalles Bibliográficos
Autores principales:	Hu, Can, Zhang, Xin, Wei, Wenying, Zhang, Ning, Wu, Haiming, Ma, Zhenguo, Li, Lingli, Deng, Wei, Tang, Qizhu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664099/ https://www.ncbi.nlm.nih.gov/pubmed/31384530 http://dx.doi.org/10.1016/j.apsb.2019.03.003

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