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The Gastro-protective Effect of Ginger (Zingiber officinale Roscoe) in Helicobacter pylori Positive Functional Dyspepsia
Purpose: The present study aimed to assess the effect of ginger (Zingiber officinale) powder supplementation on Helicobacter pylori eradication and improvement of dyspeptic symptoms in patients with H. pylori positive functional dyspepsia (FD). Methods: During this pilot study 15 patients with H. py...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tabriz University of Medical Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664109/ https://www.ncbi.nlm.nih.gov/pubmed/31380260 http://dx.doi.org/10.15171/apb.2019.038 |
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author | Ebrahimzadeh Attari, Vahideh Somi, Mohammad Hosein Asghari Jafarabadi, Mohammad Ostadrahimi, Alireza Moaddab, Seyed-Yaghob Lotfi, Neda |
author_facet | Ebrahimzadeh Attari, Vahideh Somi, Mohammad Hosein Asghari Jafarabadi, Mohammad Ostadrahimi, Alireza Moaddab, Seyed-Yaghob Lotfi, Neda |
author_sort | Ebrahimzadeh Attari, Vahideh |
collection | PubMed |
description | Purpose: The present study aimed to assess the effect of ginger (Zingiber officinale) powder supplementation on Helicobacter pylori eradication and improvement of dyspeptic symptoms in patients with H. pylori positive functional dyspepsia (FD). Methods: During this pilot study 15 patients with H. pylori positive FD received 3 g/d ginger powder as three 1-g tablets for 4-weeks. Dyspepsia symptoms were asked before and after the intervention using a questionnaire based on the Rome III criteria. H. pylori eradication was also assessed by a non-invasive stool antigen (HpSAg) test. Results: Ginger consumption accompanied by significant H. pylori eradication rate of 53.3% (P = 0.019) and the odds ratio (95% CI) was 8 (1.07 to 357.14). Moreover, our results showed significant changes in most of the dyspepsia symptoms after ginger supplementation. Conclusion: According to our findings, Z. officinale can be considered as a useful complementary therapy for FD. However, due to the small number of clinical trials in this area, further welldesigned clinical trials are needed to explicitly talk about its effectiveness especially about the eradication of H. pylori. |
format | Online Article Text |
id | pubmed-6664109 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Tabriz University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-66641092019-08-02 The Gastro-protective Effect of Ginger (Zingiber officinale Roscoe) in Helicobacter pylori Positive Functional Dyspepsia Ebrahimzadeh Attari, Vahideh Somi, Mohammad Hosein Asghari Jafarabadi, Mohammad Ostadrahimi, Alireza Moaddab, Seyed-Yaghob Lotfi, Neda Adv Pharm Bull Short Communication Purpose: The present study aimed to assess the effect of ginger (Zingiber officinale) powder supplementation on Helicobacter pylori eradication and improvement of dyspeptic symptoms in patients with H. pylori positive functional dyspepsia (FD). Methods: During this pilot study 15 patients with H. pylori positive FD received 3 g/d ginger powder as three 1-g tablets for 4-weeks. Dyspepsia symptoms were asked before and after the intervention using a questionnaire based on the Rome III criteria. H. pylori eradication was also assessed by a non-invasive stool antigen (HpSAg) test. Results: Ginger consumption accompanied by significant H. pylori eradication rate of 53.3% (P = 0.019) and the odds ratio (95% CI) was 8 (1.07 to 357.14). Moreover, our results showed significant changes in most of the dyspepsia symptoms after ginger supplementation. Conclusion: According to our findings, Z. officinale can be considered as a useful complementary therapy for FD. However, due to the small number of clinical trials in this area, further welldesigned clinical trials are needed to explicitly talk about its effectiveness especially about the eradication of H. pylori. Tabriz University of Medical Sciences 2019-06 2019-06-01 /pmc/articles/PMC6664109/ /pubmed/31380260 http://dx.doi.org/10.15171/apb.2019.038 Text en © 2019 The Author (s). http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution (CC BY), which permits unrestricted use, distribution, and reproduction in any medium, as long as the original authors and source are cited. No permission is required from the authors or the publishers. |
spellingShingle | Short Communication Ebrahimzadeh Attari, Vahideh Somi, Mohammad Hosein Asghari Jafarabadi, Mohammad Ostadrahimi, Alireza Moaddab, Seyed-Yaghob Lotfi, Neda The Gastro-protective Effect of Ginger (Zingiber officinale Roscoe) in Helicobacter pylori Positive Functional Dyspepsia |
title |
The Gastro-protective Effect of Ginger (Zingiber officinale Roscoe) in Helicobacter pylori Positive Functional Dyspepsia
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title_full |
The Gastro-protective Effect of Ginger (Zingiber officinale Roscoe) in Helicobacter pylori Positive Functional Dyspepsia
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title_fullStr |
The Gastro-protective Effect of Ginger (Zingiber officinale Roscoe) in Helicobacter pylori Positive Functional Dyspepsia
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title_full_unstemmed |
The Gastro-protective Effect of Ginger (Zingiber officinale Roscoe) in Helicobacter pylori Positive Functional Dyspepsia
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title_short |
The Gastro-protective Effect of Ginger (Zingiber officinale Roscoe) in Helicobacter pylori Positive Functional Dyspepsia
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title_sort | gastro-protective effect of ginger (zingiber officinale roscoe) in helicobacter pylori positive functional dyspepsia |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664109/ https://www.ncbi.nlm.nih.gov/pubmed/31380260 http://dx.doi.org/10.15171/apb.2019.038 |
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