Cargando…
Astrocytes Modify Migration of PBMCs Induced by β-Amyloid in a Blood-Brain Barrier in vitro Model
BACKGROUND: The brain is protected by the blood-brain barrier (BBB), constituted by endothelial cells supported by pericytes and astrocytes. In Alzheimer’s disease a dysregulation of the BBB occurs since the early phases of the disease leading to an increased access of solutes and immune cells that...
Autores principales: | Spampinato, Simona Federica, Merlo, Sara, Fagone, Evelina, Fruciano, Mary, Barbagallo, Cristina, Kanda, Takashi, Sano, Yasuteru, Purrello, Michele, Vancheri, Carlo, Ragusa, Marco, Sortino, Maria Angela |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664149/ https://www.ncbi.nlm.nih.gov/pubmed/31396056 http://dx.doi.org/10.3389/fncel.2019.00337 |
Ejemplares similares
-
Reciprocal Interplay Between Astrocytes and CD4+ Cells Affects Blood-Brain Barrier and Neuronal Function in Response to β Amyloid
por: Spampinato, Simona Federica, et al.
Publicado: (2020) -
Decreased Astrocytic CCL2 Accounts for BAF-312 Effect on PBMCs Transendothelial Migration Through a Blood Brain Barrier in Vitro Model
por: Spampinato, Simona F., et al.
Publicado: (2021) -
The contribution of microglia to early synaptic compensatory responses that precede β-amyloid-induced neuronal death
por: Merlo, Sara, et al.
Publicado: (2018) -
Astrocyte-Derived Paracrine Signals: Relevance for Neurogenic Niche Regulation and Blood–Brain Barrier Integrity
por: Spampinato, Simona Federica, et al.
Publicado: (2019) -
Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli?
por: Spampinato, Simona F., et al.
Publicado: (2015)